Long range chromosome organization in Escherichia coli: The position of the replication origin defines the non-structured regions and the Right and Left macrodomains.
The Escherichia coli chromosome is organized into four macrodomains (Ori, Ter, Right and Left) and two non-structured regions.This organization influences the segregation of sister chromatids, the mobility of chromosomal DNA, and the cellular localization of the chromosome.The organization of the Ter and Reamers Ori macrodomains relies on two speci